If you know about a subject, you have studied it or taken an interest in it, and understand part or all of it. Hire someone with experience, someone who knows about real estate. Possibly, "I do know that" can in fact only be used, when, you are answering the question of whether or not you know the issue at hand (or your knowledge has been called in to question, and you are answering that challenge).

Context Explanation

Let's say "out of the blue" you wanted to state that "you know that" -- and you wanted an emphatic version. This is a literal sense. Additional definitions are more figurative, "knowing someone inside out" is to know them thoroughly. "inside and out" is in Merriam Websters abridged dictionary, and is therefore not available online.

Insight Material

It does cite "inside out." "Inside and out" can mean simply the inside and the outside.